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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Curr Opin Nephrol Hypertens. 2014 Jan;23(1):1–8. doi: 10.1097/01.mnh.0000437204.84826.99

Figure 2.

Figure 2

Atomic Resolution model of ROMK. Two of four subunits are shown for clarity. HR Variants are located in the cytoplasmic domain. Inset on right shows HR variants that affect PIP2-dependent gating reside in the PIP2 binding site.