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. 2010 Jun 28;31(7):805–812. doi: 10.1038/aps.2010.65

Figure 2.

Figure 2

CD151 gene delivery promotes the proliferation, migration, tube formation of HUVECs. (A) MTT assay results after HUVECs transfected with rAAV-CD151, rAAV-anti-CD151 and rAAV-GFP. rAAV-CD151 transfection significantly enhanced HUVECs proliferation as compared with the control and GFP groups. (B) Transwell boyden chamber assays showed rAAV-CD151 transfection promoted the migration of HUVECs. (C) and (D) Matrigel test demonstrated that rAAV-CD151 transfection dramatically increased the tube formation of HUVECs. (C) Representative photomicrographs showing effect of CD151 on tube formation (×100). (D) Quantitative analysis of the effect of CD151 on tube formation. bP<0.05 vs the control group and GFP group. eP<0.05 vs the CD151 group. n=3. Mean±SEM.