. Author manuscript; available in PMC: 2015 May 1.

Published in final edited form as: Behav Brain Res. 2014 Feb 7;264:74–81. doi: 10.1016/j.bbr.2014.01.053

Table 2.

Summary of behavioral and motor tests

		WT	Fgfr1 HET	Fgf8 HET	Fgfr1/Fgf8 HET
EPM	% Open entries	19.93 ± 5.82	15.51 ± 4.06	8.77 ± 3.61	24.80 ± 7.33
EPM	% Closed entries	80.07 ± 5.82	81.78 ± 4.65	91.23 ± 3.61	75.20 ± 7.33
OF	Total distance traveled (cm)	4982 ± 185	4756 ± 284	4691 ± 179	4467 ± 178
LD	Total distance traveled in light compartment (cm)	1886 ± 92	1787 ± 107	1684 ± 117	1763 ± 119
	Latency to enter dark compartment (s)	9.00 ± 1.68	7.19 ± 1.24	5.90 ± 0.81	8.33 ± 1.40
	Total number transitions (#)	28.8 ± 1.17	25.44 ± 1.87	25.18 ± 1.28	27.68 ± 1.46
	% Time in light compartment	52.71 ± 3.55	48.31 ± 3.62	47.18 ± 3.11	49.09 ± 2.98
Grip Test	Latency to fall (s)	54.29 ± 3.48	49.25 ± 5.47	58.75 ± 0.996	52.00 ± 3.36

No significant differences between genotypes were found for any behavior or motor task listed in this table. EPM, OF, LD (n = 14–15 WT, n = 14–16 Fgfr1 HET, n = 16–22 Fgf8 HET, n = 13–19 Fgfr1/Fgf8 HET). Grip test (n = 7 WT, n = 8 Fgfr1 HET, n = 8 Fgf8 HET, n = 14 Fgfr1/Fgf8 HET). Values represent the mean ± SEM.