Table 4. P values of SNPs for male- and female-offspring nuclear families population stratification, total association, and within-family association using QTDT. BMD values are adjusted for age, height and weight; the cutoff of significance was set at P=0.0042.

	Male-offspring families		Female-offspring families
	rs1867863	rs4972504	rs1867863	rs4972504
Tests of population stratification
Lumbar spine BMD	0.316	0.276	0.962	0.397
Femoral neck BMD	0.025	0.023	0.977	0.331
Total hip BMD	0.047	0.024	0.912	0.381
Tests of total association
Lumbar spine BMD	0.635	0.365	0.787	0.566
Femoral neck BMD	0.948	0.970	0.968	0.517
Total hip BMD	0.687	0.780	0.833	0.379
Tests of within-family association
Lumbar spine BMD	0.268	0.164	0.927	0.308
Femoral neck BMD	0.044	0.047	0.964	0.244
Total hip BMD	0.053	0.036	0.989	0.229
P 1000 permutation of within-family association
Lumbar spine BMD	0.237	0.097	0.903	0.190
Femoral neck BMD	0.039	0.036	0.951	0.195
Total hip BMD	0.049	0.031	0.991	0.143