Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
p53 and p21 levels. Cell extracts were prepared from wild-type (Wt) or Nrf2−/− murine embryonic fibroblasts (MEFs) obtained from the passages depicted in the figure and then probed for p53 (A) or p21 (B) by immunoblot. Results from a representative blot are shown for each case. Genetic deletion of Nrf2 resulted in the early loss of p53 and p21, the main hallmarks of MEFs immortalization.
