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Reagent and conditions: (a) m-CPBA, toluene, reflux. (b) 2-(Piperazin-1-yl)pyrazine, DIEA, DMF, 200 °C for 20 min in microwave. (c) Zn, CaCl2, EtOH, 4 h. (d) Carboxylic acid, HATU, DIEA, DMF.
