Table 5. Plasma Protein Binding and Cytochrome P450 Inhibition of 9b.
| plasma protein binding (ultracentrifugation) | % | CYP isoform | IC50 (μM) |
|---|---|---|---|
| mouse | 98.5 | 3A4 | >25.0 |
| rat | 96.6 | 1A2 | >25.0 |
| human | 97.3 | 2D6 | >25.0 |
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