Table 2.
Clinicopathologic characteristics of patients who underwent resection for colorectal cancer liver metastases stratified for the administration of adjuvant therapy
| No adjuvant CTx | Adjuvant CTx | P value | |
|---|---|---|---|
|
n |
181 (61) |
116 (39) |
|
|
Gender |
|
|
0.11 |
| Male |
115 (64) |
84 (72) |
|
| Female |
66 (36) |
32 (28) |
|
|
Age [years] |
64 (30 – 88) |
63 (33 – 83) |
0.03 |
|
Initial stage of disease (UICC) |
|
|
0.53 |
| I |
23 (7) |
9 (8) |
|
| II |
37 (21) |
17 (15) |
|
| III |
56 (32) |
36 (31) |
|
| IV |
70 (40) |
53 (46) |
|
|
Site of primary tumor |
|
|
0.14 |
| Colon |
95 (52) |
71 (61) |
|
| Rectum |
86 (47) |
45 (39) |
|
|
CEA level [μg/l) |
12.6 (0.6 – 2032) |
18.1 (0.5 – 7606) |
0.63 |
|
Number of metastases |
|
|
0.72 |
| 1 |
99 (55) |
61 (53) |
|
| > 1 |
82 (45) |
55 (47) |
|
|
Size of largest metastasis |
|
|
0.06 |
| < 5 cm |
95 (52) |
48 (41) |
|
| ≥ 5 cm |
86 (48) |
68 (59) |
|
|
Distribution of metastases |
|
|
0.08 |
| Unilobar |
120 (67) |
66 (57) |
|
| Bilobar |
60 (33) |
55 (43) |
|
|
MSKCC clinical risk score |
|
|
0.07 |
| ≤ 2 |
111 (61) |
60 (52) |
|
| > 2 | 69 (39) | 56 (48) |
Data are presented as n (%) or median (range). CTx, Chemotherapy.