Table 4.
Multivariate analysis of factors associated with overall survival in patients who underwent potentially curative resection for colorectal cancer liver metastases stratified for patients’ MSKCC clinical risk score
| Variable | Comparison | Hazard ratio | 95% CI | P Value |
|---|---|---|---|---|
|
MSKCC clinical risk score ≤ 2 | ||||
|
Age |
- |
1.01 |
0.99 – 1.04 |
0.20 |
|
Distribution of metastasis |
Bilobar vs. unilobar |
1.80 |
1.12 – 2.92 |
0.01 |
|
Initial stage of disease (UICC) |
|
|
|
0.41 |
| 1 |
Reference |
|
|
|
| 2 |
1.96 |
0.80 – 4.81 |
0.13 |
|
| 3 |
1.92 |
0.80 – 4.59 |
0.14 |
|
| 4 |
1.52 |
0.60 – 3.83 |
0.36 |
|
|
Adjuvant chemotherapy |
Adjuvant CTx vs. no adjuvant CTx |
0.90 |
0.57 – 1.43 |
0.67 |
|
MSKCC clinical risk score > 2 | ||||
|
Age |
- |
1.00 |
0.98 – 1.03 |
0.61 |
|
Distribution of metastasis |
Bilobar vs. unilobar |
1.65 |
0.98 – 2.77 |
0.06 |
|
Initial stage of disease (UICC) |
|
|
|
0.21 |
| 1 |
Reference |
|
|
|
| 2 |
0.21 |
0.02 – 2.27 |
0.20 |
|
| 3 |
0.60 |
0.07 – 4.79 |
0.63 |
|
| 4 |
0.38 |
0.05 – 3.03 |
0.36 |
|
| Adjuvant chemotherapy | Adjuvant CTx vs. no adjuvant CTx | 0.40 | 0.23 – 0.70 | 0.001 |
CTx, Chemotherapy.