Table 2. Plasma lipids, endothelial lipase and serum cholesterol efflux capacity.
Controls | DM | |
---|---|---|
Total cholesterol (mmol/L) | 5.06 ± 0.8 | 5.06 ± 0.97 |
Triglyceride (mmol/L) | 1.00 (0.80–1.60) | 1.40 (0.90–2.10)** |
LDL cholesterol (mmol/L) | 3.04 ± 0.76 | 3.06 ± 0.88 |
HDL cholesterol (mmol/L) | 1.42 ± 0.38 | 1.14 ± 0.26** |
APOA1(g/L) | 1.44 ± 0.27 | 1.29 ± 0.23** |
APOB (g/L) | 0.88 ± 0.20 | 0.93 ± 0.23* |
EL (ng/mL) | 24.0 ± 11.3 | 27.7 ± 16.6* |
SR‐BI mediated cholesterol efflux to serum (%) | 16.68 ± 3.14 | 15.13 ± 2.46** |
ABCA1 mediated cholesterol efflux to serum (%) | 1.60 ± 0.49 | 1.56 ± 0.50 |
Values are mean ± SD or median (interquartile range). *P < 0.05, **P < 0.01 vs controls. ABCA1, adenosine triphosphate‐binding cassette transporter A1; APOA1, apolipoprotein A1; APOB, apolipoprotein B; DM, diabetes mellitus EL, endothelial lipase; HDL, high‐density lipoprotein; LDL, low‐density lipoprotein; SR‐BI, scavenger receptor class B type I.