Figure 1.

The expression of de novo lipogenesis associated genes among different AT depots and infection models. The gene expression fold changes were calculated from the microarray analysis data as described in the Methods section. Differences in gene expression in the inguinal and epididymal AT transcriptomes induced by A) recurrent A. actinomycetemcomintas infection, B) chronic C. pneumoniae infection and C) combined recurrent A. actinomycetemcomintas and C. pneumoniae infections. The changes were statistically non-significant after false discovery rate correction. Acaca, acetyl-Coenzyme A carboxylase alpha; Elovl6, ELOVL family member 6, elongation of long chain fatty acids (yeast); Fasn, fatty acid synthase; Pcx, pyruvate carboxylase; Pparg, peroxisome proliferator activated receptor γ; Scd1, stearoyl-Coenzyme A desaturase 1; Scd2, stearoyl-Coenzyme A desaturase 2.