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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Ann Thorac Surg. 2014 Feb 25;97(4):1142–1148. doi: 10.1016/j.athoracsur.2013.12.043

Table 4.

Pathology of false negative and false positive lesions

Malignant FDG-PET Non-Avid False Negatives (%) *
Adenocarcinoma 62 (62)
Squamous Cell 11 (11)
Carcinoma in situ 11 (11)
Carcinoid/Neuroendocrine 9 (9)
Other NSCLC 4 (4)
Other Cancer 1 (1)
Small Cell 1 (1)
Unknown 2 (2)

Benign FDG-PET Avid False Positives (%)

Granuloma** 55 (69)
Benign Tumor 8 (10)
Active Infectious disease*** 9 (11)
Fibrosis 4 (5)
Other 4 (5)
*

11 of the false negatives were <1cm

**

Granuloma includes histoplasmosis, atypical mycobacteria, blastomycosis, cryptococcus, coccidiodomycosis, aspergillosis and nonspecific granulomas.

***

Infectious disease includes active Mycobacterium tuberculosis and active pneumonia