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. 2014 Apr 24;142(2):216–226. doi: 10.1111/imm.12242

Figure 4.

Figure 4

Kallistatin treatment reduces high mobility group box-1 (HMGB1), toll-like receptor-4 (TLR4), vascular cell adhesion molecule 1 (VCAM-1) and intercellular adhesion molecule 1 (ICAM-1) expression in kidney tissue of caecal ligation and puncture mice. Levels of (a, c) HMGB1, (b, c) TLR4, (d) VCAM-1 and (e) ICAM-1 were significantly reduced in kallistatin-treated mice (n = 3 to n = 6). Data are expressed as means ± standard error of the mean (SE). * P < 0·05 compared with the other groups.