Figure 2.

Pattern recognition receptor (PRR) expression profiles of dendritic cell (DC) subsets do not differ between allergic individuals and non-allergic controls. Expression of 12 PRRs on distinct DC subsets were analysed and compared between allergic (n = 13) and non-allergic (n = 6) individuals using a support vector machine (SVM) algorithm and leave-one-out cross-validation procedure. The decision values obtained from the comparisons are illustrated in receiver operating characteristic curves with the area under the curve (AUC) value corresponding to the ability of the SVM to discriminate between the allergic and non-allergic donors. An AUC value of one corresponds to perfect separation between groups, but values close to one were not obtained for any of the DC subsets and allergic and non-allergic individuals therefore express similar PRR profiles.