Table 1.
Baseline characteristics of 81 PHID patients, ALTADIH Cohort, 2007-2010
| Characteristics | Distribution | |
|---|---|---|
|
Sociodemographic data |
|
|
| Female, n (%) |
48 |
(59) |
| Median age at diagnosis in years (interquartile range) |
41 (35–54) |
|
| Median age at enrolment in years (interquartile range) |
46 (38–58) |
|
|
Clinical data, n (%) |
|
|
|
Respiratory tract infections |
|
|
| Otitis, sinusitis, nasopharyngitis, polyposis |
64 |
(79) |
| Bronchitis, pneumonia |
65 |
(80) |
| Bronchiectasis |
21 |
(26) |
|
Gastrointestinal tract infection |
|
|
| Chronic diarrhea |
16 |
(20) |
| Acute diarrhea |
13 |
(16) |
| Lambliasis |
11 |
(14) |
|
PHID complications: at least one of the following |
31 |
(38) |
| Lymphoid hyperplasia |
16 |
(20) |
| Splenomegaly |
14 |
(17) |
| Autoimmune manifestations* |
14 |
(17) |
| Granulomatous disease† |
9 |
(11) |
| Villous atrophy |
5 |
(6) |
| Chronic inflammatory intestinal disease |
4 |
(5) |
|
Therapeutic data, n (%) |
|
|
| Subcutaneous or intravenous immunoglobulin substitution | 66 | (81) |
*Autoimmune anemia, autoimmune neutropenia, autoimmune thrombocytopenia, Hashimoto thyroiditis, Goujerot-Sjögren syndrome.
†Location of biopsy proven granuloma: lymph node, digestive tract, spleen, bone narrow.