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. 2014 Mar 12;15:13. doi: 10.1186/1471-2172-15-13

Table 5.

Immunological markers association with CVID complications

  Unit Odds ratio 95% confidence interval p-value
B cells
  
  
  
  
CD19+
 cells/mm3
 0.65
 [0.36; 1.15]
 0.1373
CD27-IgD+
 % CD19+
 1.49
 [0.89; 2.48]
 0.1310
CD27-IgD-
 % CD19+
 0.54
 [0.24; 1.23]
 0.1401
CD27 + IgD+
 % CD19+
 0.62
 [0.34; 1.12]
 0.1124
CD27 + IgD-
 % CD19+
 0.93
 [0.29; 0.86]
 0.0119
T cells
  
  
  
  
CD3+
 cells/mm3
 0.68
 [0.40; 1.17]
 0,1646
CD4+
 cells/mm3
 0.45
 [0.26; 0.78 ]
 0,0046
CD8+
 cells/mm3
 1.04
 [0.66; 1.62 ]
 0.8818
CD4+/CD8+ ratio
  
 0.99
 [0.63; 1.56 ]
 0.9649
CD8+ T cells
 
  
  
  
CD45RA + CCR7+
 % CD8+
 0.69
 [0.43; 1.13]
 0.1385
CD45RA-CCR7+
 % CD8+
 0.75
 [0.46; 1.25]
 0.2710
CD45RA-CCR7-
 % CD8+
 1.38
 [0.86; 2.20]
 0.1800
CD45RA + CCR7-
 % CD8+
 0.77
 [0.48; 1.23]
 0.2666
CD8 + CD57+
 % CD8+
 1.30
 [0.83; 2.06]
 0.2567
Activated T cells
 
  
  
  
CD3 + HLA-DR+
 % CD3+
 2.99
 [1.56; 5.73]
 0.0010
CD4 + HLA-DR+
 % CD4+
 2.70
 [1.40; 5.23]
 0.0032
CD8 + HLA-DR+
 % CD8+
 2.75
 [1.54; 4.90]
 0.0006
Regulatory T cells
 cells/mm3
 0.41
 [0.22; 0.78]
 0.0065
Natural Killer cells
 cells/mm3
 0.75
 [0.46; 1.21]
 0.2369
Dendritic cells
  
  
  
  
Myeloid
 /ml
 0.65
 [0.36; 1.17]
 0.1532
Plasmacytoid
 /ml
 0.37
 [0.18; 0.73]
 0.0046
Gammadelta cells
 cells/mm3
 1.30
 [0.79; 2.13]
 0.3028
Gammadelta 2 cells % GD 0.52 [0.32; 0.85] 0.0087

Univariable logistic regression analysis (Odds ratio per 1 standard deviation).

ALTADIH Cohort, 2007-2010.