Table 1.
Correlation between chemerin gene expression in ovaries of PCO rats with insulin, glucose, HOMA-IR index, testosterone, progesterone and body mass index (BMI) after PCO induction and treatment of PCO rats with pioglitazone and metformin
| ΔChemerin mRNA (after treatment) |
Chemerin mRNA (PCOS) |
Variables |
||
|---|---|---|---|---|
| p | r | p | r | |
| 0.0847 |
0.361 |
0.0327 |
0.661* |
Glucose (mg/dl) |
| 0.0432 |
0.578* |
0.0087 |
0.754** |
Insulin (μg/l) |
| 0.0916 |
0.291 |
0.0414 |
0.523* |
Testosterone (ng/ml) |
| 0.0382 |
0.619* |
0.0091 |
0.827** |
Progesterone (ng/ml) |
| 0.0478 |
0.564* |
0.0276 |
0.678* |
HOMA-IR |
| 0.0739 | 0.378 | 0.0312 | 0.654* | BMI |
*Correlation is significant at the 0.05 level.
**Correlation is significant at the 0.01 level.
Correlation coefficient (r) and statistical significance (P) are indicated.
(Δ) change in chemerin gene expression level after treatment.