Figure 4. The differentially expressed genes in U266/CD9 and U266/Vector cells tested by genome-wide expression profile chip experiments and the analysis of related signaling pathways.

CD9 expression mainly affected three important signaling pathways in MM. They are the endoplasmic reticulum stress pathway, cell adhesion related signaling pathways and osteoclast differentiation related signaling pathway, respectively (A). The degree of differentially expressed genes and p values were also analysed (B).