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. 2013 May 29;5(1):15–20. doi: 10.4161/bioe.25158

Table 1. Cellular locations for recombinant protein production in various plant host and types of proteases identified at these locations.

Host Protein Compartment Protease References
Solanum tuberosum cv Desireé Sea anemone equistatin Secretory pathway, lytic vacuole, ER Arginine/lysine-specific, legumain-type Asn-specific cysteine 1
Nicotiana tabacum cv Samsun NN Monoclonal mouse IgG1 Apoplast Cysteine, aspartic 2
Nicotiana tabacum L. Cv. Samsun Glutathione reductase Cytosol Cysteine 3
Solanum tuberosum plantlets, cv Kennebec human α1-antichymotrypsin Cytosol Aspartic, serine 4
Oryza sativa L. cv Dongin Human granulocyte–macrophage colony stimulating factor Secretory pathway Cysteine 5
Oryza sativa L. cv Dongin Synthetic serine proteinase inhibitor II gene Extracellular Serine 6
Oryza sativa L. cv Dongin Human granulocyte–macrophage colony stimulating factor Extracellular Serine 7
Solanum tuberosum L., cv Kennebec Bovine aprotinin Cytosol, ER, apoplast Serine 8
Nicotiana tabacum cv BY-2 Human α1-antichymotrypsin ER, Golgi, apoplast, extracellular Serine 9
Nicotiana tabacum L. Oryzacystatin-1 ER, chloroplast Cysteine 10
Nicotiana tabacum (var. xanthi) Human IgG1κ antibody Apoplast Cysteine, aspartic, serine 11 , 12
Solanum tuberosum L., cv Kennebec Tomato cathepsin D inhibitor (CDI), Bovine aprotinin Cytosol, ER Serine 13
Nicotiana tabacum cv “81V9” Spider dragline silk ER Serine 14
Solanum tuberosum L., cv Kennebec Tomato cathepsin D inhibitor (SlCDI) Cytosol Aspartic, serine 15
Nicotiana tabacum Monoclonal antibodies Secretory pathway Serine 16
Solanum lycopersium var PED Human α1-proteinase inhibitor ER, apoplast, vacuole, cytosol Serine 17