Table 3. Nominally associated mt haplogroups in discovery and follow-up in confirmation.
Discovery | Confirmation | |||||||||
Haplo-group a | Frequency Cases [%] | Frequency Controls [%] | Odds Ratio | Confidence Interval b | p-value c | Frequency Cases [%] | Frequency Controls [%] | Odds Ratio | Confidence Interval b | p- value c |
all | n = 1,114 | n = 422 | n = 1,623 | n = 2,271 | ||||||
W | 1.17 | 2.84 | 0.40 | 0.17–0.97 | 0.034 | 2.71 | 1.94 | 1.41 | 0.90–2.20 | 0.126 |
males | n = 491 | n = 163 | n = 793 | n = 890 | ||||||
W | 0.41 | 3.07 | 0.13 | 0.01–0.81 | 0.012 | 2.14 | 1.69 | 1.28 | 0.60–2.77 | 0.592 |
females | n = 623 | n = 259 | n = 830 | n = 1,381 | ||||||
J | 8.19 | 13.13 | 0.58 | 0.36–0.94 | 0.032 | 10.96 | 9.27 | 1.20 | 0.89–1.61 | 0.211 |
only individuals with HaploGrep's quality ≥90% were included (∼96% of all individuals).
95% confidence interval for odds ratio.
Fisher's exact test, two-sided, p-values below 0.05 are highlighted in bold.