Skip to main content
. Author manuscript; available in PMC: 2014 May 2.
Published in final edited form as: Cell Stem Cell. 2010 Oct 8;7(4):483–495. doi: 10.1016/j.stem.2010.08.014

Figure 3. Cell identity of the SGZ apoptotic cells.

Figure 3

Confocal orthogonal projections of apoptotic cells, identified by pyknosis/karyorrhexis, express different cell-type specific biomarkers in the young adult neurogenic SGZ. Low magnification images of all immunolabeling data can be found in Fig. S3.

(A) Apoptotic cell expressing nestin-GFP.

(B) Apoptotic cell expressing PSA-NCAM.

(C) Apoptotic cell expressing nestin-GFP and PSA-NCAM.

(D) Apoptotic cell expressing POMC-EGFP but not DCX.

(E) Apoptotic cell expressing Prox1 but not NeuN.

(F) Apoptotic cell expressing PECAM1 but not hGFAP-GFP. A capillary with PECAM1+ endothelial cell surrounded by hGFAP-GFP+ astrocytic terminal feet is nearby (arrows).

(G) Apoptotic cell not expressing either MBP or GFAP.

(H) Fraction of SGZ apoptotic cells expressing each of the different cell-type markers shown above. The majority of the apoptotic cells expresses markers of cells found in early stages of the neurogenic cascade.

Scale bars: 10μm. ND, non-detectable. Bars represent mean ± SEM. Arrows, capillary.