Table 1. Summary of septin amino acids that interact with guanine nucleosides and FCF.
| SEPT2 - GDP | SEPT2 - GppNHp | SEPT3 - GDP | SEPT7 - GDP | ||||||
| GDP | FCF | GppNHp | FCF 113* | FCF 73 | GDP | FCF | GDP | FCF 57 | FCF 37 |
| GLY 47 (A)** | PRO 155 (B) | SER 46 (A) | GLY 49 (A) | SER 46 (A) | LYS 74 (A) | SER 75 (A) | GLY 41 (C) | GLY 43 (C) | GLY 41 (C) |
| LYS 50 (A) | GLY 157 (B) | LEU 48 (A) | THR 52 (A) | LEU 48 (A) | SER 75 (A) | THR 76 (A) | LEU 42 (C) | THR 46 (C) | SER 45 (C) |
| SER 51 (A) | LYS 183 (A) | GLY 49 (A) | ASP 185 (A) | SER 51 (A) | THR 76 (A) | PRO 180 (B) | GLY 43 (C) | ASP 178 (C) | THR 46 (C) |
| THR 52 (A) | THR 186 (B) | LYS 50 (A) | GLU 191 (B) | THR 78 (A) | ASP 210 (A) | THR 181 (B) | LYS 44 (C) | GLU 184 (A) | ASP 94 (C) |
| ASP 185 (A) | THR 186 (A) | SER 51 (A) | GLY 241 (A) | ASP 101 (A) | THR 211 (B) | THR 211 (B) | SER 45 (C) | GLY 231 (C) | SER 149 (A) |
| THR 186 (B) | GLU 191 (B) | THR 52 (A) | ARG 256 (A) | THR 102 (A) | GLY 265 (A) | THR 46 (C) | ARG 246 (C) | ||
| GLU 191 (B) | GLY 241 (A) | THR 78 (A) | ARG 280 (A) | SER 149 (A) | |||||
| GLY 241 (A) | GLY 104 (A) | ASP 178 (C) | |||||||
| LYS183 (A) | THR 179 (A) | ||||||||
| ASP 185 (A) | GLU 184 (A) | ||||||||
| THR 186 (B) | GLY 231 (C) | ||||||||
| GLU 191 (B) | ARG 246 (C) | ||||||||
| GLY 241 (A) | |||||||||
| ARG 256 (A) | |||||||||
*Numbers correspond to the docked poses within the cluster of conformations shown in Figure 3.
**Parentheses indicate the corresponding protomer of each amino acid.