Figure 3. ICE-induced fat accumulation does not require increased food intake.

(A) Daily food intake of each mouse was measured during ICE. (B) During ICE, daily food supply was restricted the average amount prior to ICE. Body composition was measured daily before each time of cold exposure. Data presented are mean ±SEM, n = 6, *p<0.05 day 0 (A) or diet-restricted control vs. ICE mice at a given time point (B); # p<0.05 vs. day 1 for the same cohort.