Table 1.

Clinical characteristics of patients

Patient No.	Sex	Age (y)	Pathology at Initial Diagnosis	Initial WHO grade	Pathology at recurrence	WHO grade at recurrence	Initial therapy	Prior treatments	Time from initial diagnosis (d)	PFS (d)	OS (d)
1	M	69	GBM	4	GBM	4	Chemotherapy/XRT	1	76	81	81
2	F	65	GBM	4	GBM	4	Chemotherapy/XRT	2	578	78	107
3	M	65	AA	3	AA	3	Chemotherapy/XRT	1	656	96	142
4	F	59	GBM	4	GBM	4	Chemotherapy/XRT	1	322	42	169
5	M	64	GBM	4	GBM	4	Chemotherapy/XRT	1	178	70	234
6	M	37	AA	3	GBM	4	Chemotherapy	2	4225	62	292
7	M	68	GBM	4	GBM	4	Chemotherapy/XRT	2	332	218	315
8	F	35	AA	3	GBM	4	XRT	3	2804	65	318
9	F	54	GBM	4	GBM	4	Chemotherapy/XRT	1	91	226	343
10	M	45	GBM	4	GBM	4	Chemotherapy/XRT	1	132	74	344
11	M	26	AA	3	GBM	4	Chemotherapy	3	462	96	364
12	F	40	GBM	4	GBM	4	Chemotherapy/XRT	1	462	44	366
13	F	47	GBM	4	GBM	4	Chemotherapy/XRT	1	160	176	374
14	M	68	GBM	4	GBM	4	Chemotherapy/XRT	1	488	343	383
15	F	70	GBM	4	GBM	4	Chemotherapy/XRT	1	362	184	395
16	F	61	GBM	4	GBM	4	Chemotherapy/XRT	2	719	137	400
17	F	37	GBM	4	GBM	4	Chemotherapy/XRT	1	126	304	460
18	M	57	GBM	4	GBM	4	Chemotherapy/XRT	1	1338	135	601
19	F	62	GBM	4	GBM	4	Chemotherapy/XRT	1	316	273	709
20	M	76	GBM	4	GBM	4	Chemotherapy/XRT	1	134	588	978
21	M	46	GBM	4	GBM	4	Chemotherapy/XRT	1	230	554	1054

^*Time from initial diagnosis is the number of days from initial diagnosis to start of treatment in current study.

^†GBM = glioblastoma multiforme; AA = anaplastic astrocytoma; XRT = radiation therapy.