. Author manuscript; available in PMC: 2015 Jun 1.

Published in final edited form as: Eur J Nucl Med Mol Imaging. 2014 Mar 7;41(6):1199–1209. doi: 10.1007/s00259-013-2678-2

Table 3.

Parameter estimates from MLR model using information from FLT only (absolute values and changes).

Multiple Linear Regression Model for Predicting Overall Survival (MLR-1)
Predictor Variable	Parameter Estimates	P-value
FLT V_d absolute value at S2	−443.29	<.0001
FLT k₄ ratio (S2/S1)	+158.44	<.0001
FLT k₂ ratio (S3/S2)	+289.66	<.0001
Intercept	+87.95	0.22

R² = 0.85, adjusted-R² = 0.82, root MSE = 106 days, and the average variance inflation factors were 1.0.

S1 = Baseline FLT PET, S2 = FLT PET at 2 weeks after start of treatment, S3 = FLT PET at 6 weeks after start of treatment.