Table 2.
Baseline Characteristics of the Study Group
| Variable | All | IL-1(+) | IL-1(−) | P-value IL-1 effect |
|---|---|---|---|---|
| Number | 499 | 299 | 200 | - |
| Age - yr | 60.0±10.9 | 59.6±11.1 | 60.6±10.7 | 0.82 |
| Female sex - no. (%) | 190 (38) | 111 (37) | 79 (40) | 0.59 |
| White race - no. (%) | 485 (97) | 294 (98) | 191 (96) | 0.51 |
| Hypertension - no. (%) | 230 (46) | 140 (47) | 90 (45) | 0.69 |
| Current smoker - no. (%) | 40 (8) | 24 (8) | 16 (8) | 0.99 |
| Previous myocardial infarction -no. (%) | 77 (15) | 53 (18) | 24 (12) | 0.08 |
| Congestive heart failure -no. (%) | 59 (12) | 32 (11) | 27 (14) | 0.35 |
| Family history of CAD - no.(%) | 126 (25) | 76 (25) | 50 (25) | 0.92 |
| Extent of disease | 0.79 | |||
| No disease | 122(24) | 71(24) | 51(26) | |
| Mild disease | 109(22) | 68(23) | 41(20) | |
| 1-vessel | 84(17) | 46(15) | 38(19) | |
| 2-disease | 80(16) | 50(17) | 30(15) | |
| 3-disease | 104(21) | 64(21) | 40(20) | |
| Lipid levels - mg/dl | ||||
| Total cholesterol | 207±45 | 208±46 | 206±43 | 0.57 |
| LDL cholesterol | 125±37 | 124±35 | 125±37 | 0.81 |
| HDL cholesterol | 48±15 | 48±15 | 48±14 | 0.94 |
| Triglycerides | ||||
| Median | 153 | 154 | 151 | 0.48 |
| Interquartile range | 112–207 | 113–220 | 106–200 | |
| Apolipoprotein B-100 | 98±21 | 98±20 | 98±22 | 0.91 |
| Apolipoprotein AI | 132±26 | 132±27 | 131±24 | 0.48 |
| Lipoprotein (a) – mg/dl | ||||
| Median | 21.1 | 21.5 | 20.0 | 0.96 |
| Interquartile range | 8.7–39.6 | 9.2–38.4 | 7.7–42.3 | |
| OxPL/apoB - RLU | ||||
| Median | 6268 | 6268 | 6121 | 0.96 |
| Interquartile range | 3381–20829 | 3361–20620 | 3414–20843 | |
| hsCRP - mg/liter | ||||
| Median | 2.9 | 3.1 | 2.3 | 0.057 |
| Interquartile range | 1.2–6.7 | 1.3–7.3 | 1.0–6.1 | |