Table 3.

Odds Ratios for CAD (>50% DS) According to Quartiles for Oxidized Phospholipid/ApoB in IL-1 Genotype Positive and IL-1 Genotype Negative Patients, According to All Ages, ≤60 years Old and ≥60 Years Old

Patient Group	All Patients			IL-1 Genotype Positive			IL-1 Genotype Negative
All ages	Total No.	No. with CAD (%)	OR (95% CI)	Total No.	No. with CAD (%)	OR (95% CI)	Total No.	No. with CAD (%)	OR (95% CI)
Quartile I	125	59 (47)	1.00	77	35 (46)	1.00	48	24 (50)	1.00
Quartile II	125	62 (50)	1.10 (0.67–1.81)	73	36 (49)	1.17 (0.62–2.22)	52	26 (50)	1.00 (0.46–2.19)
Quartile III	125	68 (54)	1.34 (0.81–2.19)	75	37 (49)	1.17 (0.62–2.21)	50	31 (62)	1.63 (0.73–3.65)
Quartile IV	124	79 (64)	1.96 (1.18–3.26)	74	52 (70)	2.84 (1.45–5.55)	50	27 (54)	1.17 (0.53–2.60)
OR (95%CI) for trend			1.25 (1.06–1.46)			1.35 (1.10–1.66)			1.10 (0.86–1.42)
P for trend			0.007			0.004			0.45
Age ≤60 yr
Quartile I	60	19 (33)	1.00	33	9 (27)	1.00	27	12 (44)	1.00
Quartile II	52	17 (32)	0.75 (0.34 – 1.67)	32	8 (25)	0.89 (0.29 – 2.69)	20	7 (35)	0.67 (0.20–2.22)
Quartile III	64	27 (45)	1.64 (0.80 – 3.38)	43	18 (42)	1.92 (0.73 – 5.10)	21	12 (57)	1.67 (0.53–5.27)
Quartile IV	63	41 (60)	2.82 (1.36 – 5.87)	40	29 (73)	7.03 (2.50 – 19.77)	23	9 (39)	0.80 (0.26–2.49)
OR (95%CI) for trend			1.48 (1.17–1.87)			1.99 (1.43–2.78)			1.01 (0.71–1.45)
P for trend			0.001			<0.001			0.94
Age >60 yr
Quartile I	65	40 (59)	1.00	44	26 (59)	1.00	21	12 (57)	1.00
Quartile II	73	47 (65)	1.28 (0.65–2.55)	41	28 (68)	1.49 (0.61–3.64)	32	19 (59)	1.10 (0.36–3.35)
Quartile III	61	41 (62)	1.17 (0.57–2.40)	32	19 (59)	1.01 (0.40–2.56)	29	19 (66)	1.43 (0.45–4.52)
Quartile IV	61	38 (67)	1.46 (0.70–3.02)	34	23 (68)	1.45 (0.57–3.69)	27	18 (67)	1.50 (0.46–4.87)
OR (95%CI) for trend			1.11 (0.88–1.39)			1.08 (0.80–1.45)			1.16 (0.81–1.68)
P for trend			0.38			0.61			0.42