Table 4.

Odds Ratios for CAD (>50% DS) According to Quartiles for Lp(a) in IL-1 Genotype Positive and IL-1 Genotype Negative Patients, According to All Ages, ≤60 years Old and ≥60 Years Old

Patient Group	All Patients			IL-1 Genotype Positive			IL-1 Genotype Negative
All ages	Total No.	No. with CAD (%)	OR (95% CI)	Tot al No.	No. with CAD (%)	OR (95% CI)	Total N	No. with CAD (%)	OR (95% CI)
Quartile I	125	55 (44)	1.00	70	30 (43)	1.00	55	25 (46)	1.00
Quartile II	125	62 (50)	1.25 (0.76–2.06)	77	37 (48)	1.23 (0.64–2.37)	48	25 (52)	1.30 (0.60–2.83)
Quartile III	125	68 (54)	1.52 (0.92–2.50)	84	42 (50)	1.33 (0.70–2.52)	41	26 (63)	2.08 (0.91–4.76)
Quartile IV	124	83 (67)	2.58(1.54–4.31)	68	51 (75)	4.00 (1.94–8.26)	56	32 (57)	1.60 (0.76–3.39)
OR (95%CI) for trend			1.35 (1.15–1.59)			1.49 (1.20–1.85)			1.20 (0.94–1.52)
P for trend			<0.001			<0.001			0.14
Age >60 yr
Quartile I	65	38 (58)	1.00	38	22 (58)	1.00	27	15 (56)	1.00
Quartile II	68	43 (62)	1.30 (0.65–2.61)	41	27 (66)	1.40 (0.56–3.49)	27	16 (59)	1.16 (0.40–3.42)
Quartile III	67	42 (61)	1.21 (0.56–2.24)	40	23 (58)	0.98 (0.40–2.42)	27	17 (63)	1.36 (0.46–4.04)
Quartile IV	60	44 (72)	2.08 (0.98–4.42)	32	24 (75)	2.18 (0.78–6.09)	28	20 (71)	2.00 (0.65–6.11)
OR (95%CI) for trend			1.21 (0.96–1.53)			1.19 (0.87–1.62)			1.25 (0.88–1.77)
P for trend			P=0.10			P=0.27			P=0.22