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24 hour food intake in mice maintained on HFD diet ad lib throughout the study or weight reduced by 20% prior to drug administration measured at 12–13 weeks of drug treatment during calorimetry assessment (TSE LabMaster system). Mean body weight is provided for each group.
Nominal doses of AZD2820 - High : 53.4 nmol/day; Medium : 10.8 nmol/day; Low : 2.64 nmol/day. Each data point represents mean 24 hr food intake for each group with SEM.
