Table 3.
Urinary BPA and phthalate concentrations and fecundability odds ratios by partner, LIFE Study.
| Chemical (ng/mL) | Female Partners (n=454) | Male Partners (n=439) | ||||
|---|---|---|---|---|---|---|
| Unadjusted | Adjusteda | Adjustedb | Unadjusted | Adjusteda | Adjustedb | |
| BPA | 0.93 (0.82, 1.06) | 0.94 (0.82, 1.07) | 0.98 (0.86, 1.13) | 1.04 (0.92, 1.17) | 1.00 (0.89, 1.14) | 1.04 (0.91, 1.18) |
| mMP | 0.95 (0.84, 1.07) | 0.96 (0.84, 1.10) | 0.93 (0.81, 1.08) | 0.89 (0.79, 1.01) | 0.84 (0.73, 0.96)* | 0.80 (0.70, 0.93)** |
| mEP | 0.95 (0.84, 1.07) | 0.96 (0.83, 1.10) | 0.97 (0.84, 1.12) | 1.06 (0.94, 1.21) | 1.02 (0.87, 1.18) | 1.01 (0.86, 1.18) |
| mCPP | 1.07 (0.95, 1.21) | 1.21 (1.01, 1.44)* | 1.20 (1.00, 1.43)* | 1.07 (0.95, 1.21) | 1.03 (0.90, 1.19) | 0.98 (0.85, 1.13) |
| mBP | 0.93 (0.83, 1.05) | 0.92 (0.76, 1.11) | 0.93 (0.77, 1.12) | 0.95 (0.85, 1.07) | 0.83 (0.71, 0.98)* | 0.82 (0.70, 0.97)* |
| miBP | 0.97 (0.86, 1.09) | 1.00 (0.83, 1.19) | 0.95 (0.78, 1.14) | 1.00 (0.89, 1.13) | 0.90 (0.76, 1.06) | 0.88 (0.74, 1.04) |
| mECPP | 0.99 (0.88, 1.11) | 1.02 (0.88, 1.19) | 1.05 (0.90, 1.22) | 0.99 (0.87, 1.11) | 0.92 (0.80, 1.06) | 0.89 (0.77, 1.03) |
| mCMHP | 0.98 (0.87, 1.10) | 1.01 (0.87, 1.18) | 1.02 (0.87, 1.19) | 0.99 (0.88, 1.11) | 0.92 (0.80, 1.06) | 0.88 (0.76, 1.02) |
| mEHHP | 0.99 (0.88, 1.12) | 1.03 (0.89, 1.18) | 1.06 (0.92, 1.22) | 0.99 (0.88, 1.12) | 0.95 (0.83, 1.09) | 0.93 (0.82, 1.07) |
| mEOHP | 1.00 (0.89, 1.13) | 1.04 (0.90, 1.22) | 1.06 (0.91, 1.24) | 0.99 (0.88, 1.12) | 0.94 (0.82, 1.08) | 0.91 (0.79, 1.05) |
| mCHP | 1.03 (0.92, 1.16) | 1.04 (0.92, 1.17) | 1.06 (0.95, 1.20) | 1.06 (0.95, 1.18) | 1.06 (0.95, 1.18) | 1.07 (0.96, 1.20) |
| mBzP | 0.93 (0.82, 1.05) | 0.93 (0.77, 1.11) | 0.94 (0.79, 1.13) | 0.92 (0.81, 1.05) | 0.77 (0.65, 0.92)** | 0.77 (0.65, 0.92)** |
| mEHP | 0.96 (0.86, 1.08) | 0.97 (0.86, 1.10) | 0.99 (0.87, 1.12) | 1.01 (0.90, 1.13) | 0.99 (0.88, 1.11) | 0.98 (0.87, 1.10) |
| mOP | 1.11 (0.99, 1.26) | 1.12 (0.99, 1.26) | 1.09 (0.96, 1.23) | 0.97 (0.85, 1.09) | 0.97 (0.85, 1.10) | 0.99 (0.87, 1.12) |
| mNP | 1.04 (0.92, 1.17) | 1.04 (0.92, 1.18) | 1.04 (0.91, 1.19) | 1.03 (0.91, 1.16) | 1.02 (0.91, 1.15) | 1.01 (0.90, 1.14) |
NOTE: Separate models were run for each chemical and partner. Chemicals were log transformed and rescaled by their standard deviations for analysis. All models accounted for left truncation or time couple was off contraception.
Modela adjusts for each partner’s urinary creatinine (continuous).
Modelb adjusts for each partner’s urinary creatinine (continuous), and also for age (continuous), BMI (continuous), serum cotinine (continuous), and research site (Michigan/Texas).
p < 0.05;
p < 0.01
mCPP, mono (3-carboxypropyl) phthalate
mMP, monomethyl phthalate
mEP, monoethyl phthalate
miBP, mono (2-isobutyl phthalate)
mBP, mono-n-butyl phthalate
mECPP, mono (2-ethyl-5-carboxyphentyl) phthalate
mCMHP, mono-[(2-carboxymethyl) hexyl] phthalate
mEOHP, mono (2-ethyl-5-oxohexyl) phthalate
mEHHP, mono (2-ethyl-5-hydroxyhexyl) phthalate
mCHP, monocyclohexyl phthalate (mCHP)
mBzP, monobenzyl phthalate
mEHP, mono (2-ethylhexyl) phthalate
mNP, mono-isonoyl phthalate
mOP, monooctyl phthalate (mOP)