Table 4.
Couples’ urinary BPA and phthalate concentrations and fecundability odds ratios, LIFE Study (n=424 couples).
| Chemical (ng/mL) | Adjusted Modela | Adjusted Modelb | ||
|---|---|---|---|---|
| Females | Males | Females | Males | |
| BPA | 0.93 (0.80,1.07) | 1.01 (0.89,1.15) | 0.96 (0.83,1.10) | 1.05 (0.92,1.20) |
| mMP | 1.00 (0.87,1.16) | 0.85 (0.73,0.98)* | 0.99 (0.85,1.15) | 0.81 (0.70,0.94)** |
| mEP | 0.96 (0.82,1.11) | 1.03 (0.88,1.20) | 0.97 (0.83,1.13) | 1.00 (0.84,1.17) |
| mCPP | 1.21 (1.01,1.46)* | 1.01 (0.88,1.17) | 1.22 (1.02,1.47)* | 0.97 (0.83,1.12) |
| mBP | 0.96 (0.79,1.16) | 0.85 (0.72,1.00) | 0.95 (0.78,1.16) | 0.87 (0.73,1.04) |
| miBP | 1.01 (0.84,1.22) | 0.90 (0.76,1.08) | 0.97 (0.80,1.18) | 0.91 (0.76,1.09) |
| mECPP | 1.04 (0.89,1.22) | 0.91 (0.79,1.06) | 1.06 (0.91,1.24) | 0.89 (0.76,1.03) |
| mCMHP | 1.02 (0.87,1.20) | 0.91 (0.78,1.05) | 1.04 (0.88,1.23) | 0.86 (0.74,1.01) |
| mEHHP | 1.03 (0.88,1.19) | 0.94 (0.82,1.08) | 1.06 (0.91,1.24) | 0.92 (0.80,1.06) |
| mEOHP | 1.07 (0.91,1.25) | 0.92 (0.80,1.06) | 1.08 (0.92,1.27) | 0.90 (0.78,1.04) |
| mCHP | 1.02 (0.91,1.15) | 1.05 (0.94,1.18) | 1.05 (0.93,1.18) | 1.07 (0.95,1.20) |
| mBzP | 0.98 (0.80,1.19) | 0.78 (0.65,0.93)** | 0.98 (0.81,1.20) | 0.80 (0.67,0.97)* |
| mEHP | 0.98 (0.86,1.11) | 1.00 (0.89,1.13) | 0.99 (0.87,1.12) | 1.02 (0.91,1.15) |
| mOP | 1.19 (1.04,1.37)* | 0.90 (0.78,1.04) | 1.18 (1.03,1.35)* | 0.92 (0.80,1.06) |
| mNP | 1.02 (0.89,1.16) | 1.01 (0.89,1.15) | 1.03 (0.90,1.18) | 1.01 (0.89,1.14) |
NOTE: Separate models were run for each chemical and partner. Chemicals were log transformed and rescaled by their standard deviations for analysis. All models accounted for left truncation or time couple was off contraception.
Modela adjusts for both partners’ chemical concentrations (continuous) and urinary creatinine (continuous).
Modelb adjusts for both partners’ chemical concentrations (continuous) and urinary creatinine (continuous), and also for female age (continuous), difference in couples’ ages (continuous), research site (Michigan/Texas), and both partners’ BMIs (continuous) and serum cotinine (continuous).
p < 0.05;
p < 0.01
mCPP, mono (3-carboxypropyl) phthalate
mMP, monomethyl phthalate
mEP, monoethyl phthalate
miBP, mono (2-isobutyl phthalate)
mBP, mono-n-butyl phthalate
mECPP, mono (2-ethyl-5-carboxyphentyl) phthalate
mCMHP, mono-[(2-carboxymethyl) hexyl] phthalate
mEOHP, mono (2-ethyl-5-oxohexyl) phthalate
mEHHP, mono (2-ethyl-5-hydroxyhexyl) phthalate
mCHP, monocyclohexyl phthalate (mCHP)
mBzP, monobenzyl phthalate
mEHP, mono (2-ethylhexyl) phthalate
mNP, mono-isonoyl phthalate
mOP, monooctyl phthalate (mOP)