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. 2014 Apr 15;106(8):1588–1595. doi: 10.1016/j.bpj.2014.02.023

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Fixed CHO cell. (a) QPM with the complete dynamic range observed in this cell. The nucleus is visible in the lower right corner. (b) Numerical high-pass filtering of the image in a to enhance the details in the phase image. Boxed areas numbered 1–3 are magnified in e. (c) Actin IF image using phalloidin-Alexa Fluor 546. (d) Tubulin IF image, using indirect staining with Alexa 488 labeling. (e) Composites of the images in b–d. A good spatial correlation between filament structures visible in high-pass QPM (b) and either actin (c) or tubulin (d) is visible in the composite images. To see this figure in color, go online.