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. 2014 Apr 15;106(8):1811–1821. doi: 10.1016/j.bpj.2014.02.030

Figure 5.

Figure 5

Pacing predictors for drift direction. (A) APD80 profiles resulting from pacing at 2 Hz in the middle of the model show inconsistent drift (arrows) toward either short or long APD regions for the three simulated conditions. (B) ERP and dV/dtmax measured at LA and PV at 2 Hz pacing for the three conditions show inconsistent drift direction. (C) Frequency-dependence of APDs. (Top) Single pixels APs in three locations across the PV-LAJ at 2- and 7-Hz pacing. (Bottom) APDs in the PV relative to those in the LA. Notably, at all pacing rates slower than 140 ms (7.14 Hz, close to the rotation frequencies in the LA and PV; see Fig. S1), the APD in the PV is shorter than in the LA (except APD90 at 140 and 500 ms). (D) APD80, ERP, MDP, and dV/dtmax in the LA and PV as measured at 1000, 500, and 140 ms pacing rate. Drift direction is also indicated (arrows on top). To see this figure in color, go online.