Table 4.
Proportion of ACT who underwent autopsy having dementia in life categorized by single or multiple pathologies.
| Neuropathologic process | % of Autopsies | Demented/Total* | % Demented |
|---|---|---|---|
| No significant cerebral pathology | 25 | 8/62 | 13 |
| Single pathology | 42 | 40/102 | 39 |
| CMI | 16 | 12/39 | 31 |
| NLB | 1 | 1/3 | 33 |
| AD | 24 | 27/60 | 45 |
| Dual Pathology | 27 | 49/67 | 73 |
| NLB + CMI | 2 | 3/5 | 60 |
| AD + NLB | 2 | 3/4 | 75 |
| AD + CMI | 18 | 43/58 | 74 |
| AD + NLB + CMI | 6 | 10/14 | 71 |
*
12 cases were excluded for missing dementia diagnosis or neuropathologic data.
CMI = presence of any cerebral microinfarcts, NLB = presence of neocortical Lewy bodies by immunohistochemistry, AD = Braak stage III through VI for neurofibrillary tangles.