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. Author manuscript; available in PMC: 2014 May 3.
Published in final edited form as: Chromosome Res. 2013 May;21(3):255–269. doi: 10.1007/s10577-013-9356-x

Figure 4. Asymmetric segregation of sister chromatids carrying different sets of histones.

Figure 4

(A) Cell cycle information: the second M phase after genetic switch is discussed here. (B) At metaphase, microtubules from mother centrosome attach to sister chromatids enriched with old H3 through unknown epigenetic marks at the centromeric region and, possibly, the asymmetric kinetochore structure. Two pairs of sister chromatids from homologous autosomes are shown here. (C) Co-segregation of sister chromatids from homologous autosomes greatly facilitates asymmetric H3 segregation in anaphase GSCs.