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Humoral autoimmunity is decreased in the absence of interleukin (IL)-17A. (a) Seven months after pristane treatment, levels of total immunoglobulin (Ig)G were decreased in IL-17A−/− mice (n = 7) compared to wild-type (WT) mice (n = 9) treated with pristane. (b) Similarly, titres of anti-dsDNA antibodies were decreased in IL-17A−/− mice. *P < 0·05; **P < 0·01.
