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. 2014 Apr 24;176(3):410–417. doi: 10.1111/cei.12290

Figure 2.

Figure 2

Antigen-specific CD4+ T cells producing any of the cytokines [interferon (IFN)-γ, interleukin (IL)-2 or tumour necrosis factor (TNF)] in 33 patients treated with TNF antagonists. Group A: 12 patients with latent tuberculosis infection (LTBI) who showed IFN-γ-level fluctuations during follow-up. Group B: 11 patients with no evidence of LTBI at baseline but showing IFN-γ-level fluctuations during follow-up. Group C: 10 patients with no evidence of LTBI at baseline and persistently negative IFN-γ levels throughout follow-up. Horizontal bars represent the median values. Statistical analysis was performed using Kruskal–Wallis analysis of variance (anova) with Dunn's post-test.