Table 3.
Cardiac MRI and spectroscopy before and after AVR
| All AS patients (n = 28) |
Follow-up AS patients (n = 14) |
Controls | ||
|---|---|---|---|---|
| Pre AVR | Post AVR | |||
| BOLD signal intensity change (%) |
5.1 ± 8.9 |
5.1 ± 8.4 |
15.6 ± 7.0* |
18.2 ± 10.1 |
| Myocardial perfusion reserve index |
1.1 ± 0.3 |
1.0 ± 0.4 |
1.6 ± 0.5* |
1.7 ± 0.3 |
| Circumferential strain (%) |
−16.4 ± 2.7 |
−16.3 ± 2.3 |
−19.4 ± 2.5* |
−21.3 ± 1.9 |
| PCr/ATP |
1.45 ± 0.21 |
1.42 ± 0.17 |
1.86 ± 0.48* |
2.00 ± 0.25 |
| Left ventricular mass index (g/m2) |
95 ± 30 |
98 ± 31 |
69 ± 17† |
56 ± 13 |
| Left ventricular ejection fraction (%) |
74 ± 7 |
76 ± 5 |
74 ± 5‡ |
69 ± 4 |
| LGE volume |
|
|
|
|
| Mass (g) |
33.2 (17.1-61.8) |
29.5 (16.7-54.2) |
17.7 (15.1-33.9)** |
- |
| Percentage myocardium (%) | 19.7 ± 11.0 | 18.1 ± 10.7 | 17.2 ± 10.8*** | - |
Values are mean ± SD or median (interquartile range). ATP indicates adenosine triphosphate; BOLD, Blood oxygen level-dependent; LGE, Late gadolinium enhancement; PCr, Phosphocreatine.
*p < 0.05 vs pre AVR and >0.05 vs controls; †p < 0.05 vs pre AVR and controls; ‡p > 0.05 vs pre AVR and <0.05 vs controls; **p < 0.05 vs pre AVR; ***p > 0.05 vs pre AVR.