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The uncorrected odds ratios (ORs) for combination genotypes of the TPA I/D and PAI 4G/5G polymorphisms in MS patients and controls.
| Genotype combinations | MS patients (n = 885) |
Controls (n = 856) |
OR (95% CI) | P |
|---|---|---|---|---|
| PAI 4G4G/TPA DD | 58 (6.6%) | 71 (8.3%) | 0.78 (0.54–1.1) | 0.167 |
| PAI 5G5G/TPA DD | 39 (4.4%) | 38 (4.4%) | 1 (0.63–1.57) | 0.974 |
| PAI 4G carrier/TPA DD | 161 (18.2%) | 185 (21.6%) | 0.81 (0.64–1.02) | 0.074 |
| PAI 5G5G/TPA I carrier | 144 (16.3%) | 105 (12.3%) | 1.39 (1.06–1.82) | 0.017 |
