Table 4.
Changes in biochemical parameters at week 12.
| Placebo (n = 20) | Herb formula (n = 20) |
P value (versus placebo) |
|||||
|---|---|---|---|---|---|---|---|
| Baseline | Week 12 | % change | Baseline | Week 12 | % change | ||
| Creatinine, μmol/L | 70.5 ± 13.1 | 68.1 ± 14.2 | −3.3 ± 9.5 | 68.7 ± 12.5 | 66.7 ± 12.6 | −2.5 ± 9.9 | 0.799 |
| Creatine kinase, U/L | 144.3 ± 72.8 | 135.7 ± 78.7 | −1.0 (−26.8, 10.1) | 144.3 ± 101.4 | 141.2 ± 73.6 | 1.2 (−7.5, 15.0) | 0.563 |
| Total protein, g/L | 75.2 ± 3.3 | 76.1 ± 3.1 | 1.3 ± 3.7 | 74.4 ± 4.2 | 75.1 ± 3.3 | 1.1 ± 3.8 | 0.860 |
| Urea, mmol/L | 4.78 ± 1.18 | 5.13 ± 1.15 | 10.2 ± 24.6 | 5.35 ± 1.29 | 5.13 ± 1.36 | −3.6 ± 15.6 | 0.041 |
| Albumin, g/L | 44.9 ± 2.4 | 45.3 ± 2.2 | 0.9 ± 4.5 | 43.5 ± 2.7 | 45.0 ± 2.6** | 3.6 ± 5.4 | 0.092 |
| Bilirubin, μmol/L | 12.6 ± 5.5 | 13.1 ± 6.8 | 4.9 ± 25.2 | 12.1 ± 4.0 | 11.9 ± 5.2 | 1.4 ± 32.2 | 0.706 |
| ALT, IU/L | 31.4 ± 9.9 | 32.1 ± 14.3 | 3.2 ± 26.1 | 24.7 ± 9.8 | 26.6 ± 10.0 | 17.7 ± 60.5 | 0.332 |
| ALP, U/L | 73.8 ± 15.8 | 73.9 ± 14.2 | 0.8 ± 7.5 | 59.5 ± 16.8 | 60.0 ± 14.4 | 2.1 ± 11.5 | 0.672 |
| Urate, mmol/L | 0.38 ± 0.09 | 0.38 ± 0.08 | 3.1 ± 12.6 | 0.34 ± 0.06 | 0.35 ± 0.07 | 0.8 ± 13.2 | 0.567 |
ALT: alanine aminotransferase; ALP: alkaline phosphatase; data are presented as mean ± SD or median (interquartile range); **P < 0.01 compared to baseline.