Table 2.
Effect of CAF3 on body weight, liver weight, and liver index in hyperlipidemic golden hamsters.
| Groups | Dose (mg/kg d−1) | Initial body weight (g) | Final body weight (g) | Liver weight (g) | Liver index (g/100 g) |
|---|---|---|---|---|---|
| NCD | — | 87.00 ± 3.83 | 96.75 ± 8.97 | 3.27 ± 0.41 | 3.33 ± 0.13 |
| HFD | — | 87.14 ± 4.74 | 124.50 ± 4.635# | 7.12 ± 0.32### | 5.73 ± 0.22### |
| HFD + XZK | 250 | 87.13 ± 2.70 | 101.50 ± 4.48* | 5.76 ± 0.32* | 5.38 ± 0.10 |
| HFD + C100 | 100 | 86.25 ± 2.34 | 104.00 ± 4.04* | 5.35 ± 0.27** | 5.06 ± 0.21 |
| HFD + C250 | 250 | 85.20 ± 2.19 | 85.00 ± 5.58*** | 4.24 ± 0.32*** | 4.47 ± 0.18*** |
| HFD + C500 | 500 | 84.60 ± 2.90 | 93.75 ± 8.12* | 5.25 ± 0.53** | 5.59 ± 0.24 |
Values are expressed as means ± SEM from 8 animals each group; NCD: normal chow diet group; HFD: high-fat diet group; HFD + XZK: high-fat diet + Xuezhikang group; HFD + C100, HFD + C250, HFD + C500: high-fat diet + CAF3 (100, 250, 500 mg/kg) group, respectively.
# P < 0.05, ### P < 0.001 compared to NCD.
*P < 0.05, **P < 0.01, ***P < 0.001 compared to HFD.