Table 3.
Effect of CAF3 on serum lipid profile in hyperlipidemic golden hamsters.
| Groups | Dose (mg/kg d−1) | TC (mmol/L) | TG (mmol/L) | HDL-C (mmol/L) | LDL-C (mmol/L) | TC/HDL-C |
|---|---|---|---|---|---|---|
| NCD | — | 1.75 ± 0.15 | 0.54 ± 0.10 | 1.16 ± 0.19 | 2.55 ± 0.25 | 1.71 ± 0.26 |
| HFD | — | 7.13 ± 1.15### | 1.52 ± 0.16### | 3.22 ± 0.28### | 9.68 ± 1.33### | 2.46 ± 0.22# |
| HFD + XZK | 250 | 4.10 ± 0.32*** | 1.04 ± 0.07* | 2.70 ± 0.17 | 5.32 ± 0.26*** | 1.66 ± 0.19* |
| HFD + C100 | 100 | 3.44 ± 0.16*** | 0.81 ± 0.08*** | 2.75 ± 0.28 | 5.96 ± 0.51*** | 1.40 ± 0.20** |
| HFD + C250 | 250 | 2.76 ± 0.18*** | 0.64 ± 0.05*** | 2.93 ± 0.15 | 3.68 ± 0.33*** | 0.91 ± 0.08*** |
| HFD + C500 | 500 | 3.69 ± 0.61*** | 1.17 ± 0.21* | 2.60 ± 0.13 | 3.04 ± 0.12*** | 1.35 ± 0.21** |
Values are expressed as means ± SEM from 8 animals each group; NCD: normal chow diet group; HFD: high-fat diet group; HFD + XZK: high-Fat diet + Xuezhikang group; HFD + C100, HFD + C250, HFD + C500: high-fat diet + CAF3 (100, 250, 500 mg/kg) group, respectively.
# P < 0.05, ### P < 0.001 compared to NCD.
*P < 0.05, **P < 0.01, ***P < 0.001 compared to HFD.