Table 4.
Effect of EPF3 on liver in hyperlipidemic golden hamsters.
| Groups | Dose (mg/kg d−1) | ALT (U/L) | AST (U/L) | SOD (U/mgprot) | GSH-Px (U/mgprot) | MDA (nmol/mgprot) |
|---|---|---|---|---|---|---|
| NCD | — | 24.61 ± 8.81 | 17.01 ± 2.87 | 38.45 ± 5.54 | 3819 ± 305 | 0.46 ± 0.01 |
| HFD | — | 117.8 ± 29.09### | 71.36 ± 12.15### | 20.42 ± 1.41## | 2160 ± 113### | 0.62 ± 0.04### |
| HFD + XZK | 250 | 31.58 ± 5.87*** | 23.41 ± 1.78*** | 32.08 ± 1.35* | 3044 ± 122* | 0.35 ± 0.02*** |
| HFD + C100 | 100 | 21.55 ± 5.50*** | 20.09 ± 2.56*** | 27.62 ± 1.78 | 3272 ± 125* | 0.35 ± 0.01*** |
| HFD + C250 | 250 | 20.20 ± 3.15*** | 16.29 ± 1.73*** | 31.57 ± 3.26* | 3693 ± 103** | 0.40 ± 0.01*** |
| HFD + C500 | 500 | 39.64 ± 13.05*** | 27.44 ± 4.06*** | 38.15 ± 2.72** | 2610 ± 100 | 0.40 ± 0.01*** |
Values are expressed as means ± SEM from 8 animals each group; NCD: normal chow diet group; HFD: high-fat diet group; HFD + XZK: high-fat diet + Xuezhikang group; HFD + C100, HFD + C250, HFD + C500: high-fat diet + CAF3 (100, 250, 500 mg/kg) group, respectively.
## P < 0.01, ### P < 0.001 compared to NCD.
*P < 0.05, **P < 0.01, ***P < 0.001 compared to HFD.