1 |
APOE |
Up |
mRNA and protein |
RT-PCR, Western blot |
Rat |
Astrocytes |
18216067, 19229075, 17548887, 15627653 |
|
|
|
2 |
BAMBI |
Down |
mRNA and protein |
RT-PCR, Western blot |
Human |
Preadipocytes |
22187378 |
|
|
|
3 |
CCND1 |
Up |
mRNA and protein |
Gene chip array, Western blot |
Human, rat |
MG63 osteoblastic cells, Rat Wister bladder tumor cells (NBT-II) |
15572039, 18189245 |
|
|
|
4 |
CDK5R1 |
Up |
mRNA and protein |
Q-PCR, Western blot |
Rat |
PC12 cells |
19249349 |
|
|
|
5 |
CDKN1A |
Up |
mRNA and protein |
RT-PCR, Western blot |
Human, mouse, rat |
Chondrocytes, REtsAF cells |
16091747, 16153144, 11779141, 10364154 |
STAT1 |
6772 |
11779141, 10364154 |
6 |
CEBPA |
Up |
mRNA and protein |
RT-PCR, Western blot |
Human, mouse |
Preadipocytes, 3T3-L1 cells |
17068114 |
|
|
|
7 |
CEBPB |
Up |
mRNA and protein |
RT-PCR, Western blot |
Human, mouse |
Preadipocytes, 3T3-L1 cells |
17068114 |
|
|
|
8 |
COX2 |
Up |
mRNA and protein |
Northern blot, ELISA |
Human, rabbit |
Cardiac muscle microvessel endothelial cells |
8790580, 2107185 |
|
|
|
9 |
EGR1 |
Up |
mRNA and protein |
Q-PCR, Western blot |
Mouse, rat |
PC12 cells, Hippocampal neuronal cell line HT22, human periodontal ligament cells |
19249349, 20649566, 18179472, 24396070 |
STAT3, SP1 |
6774, 6667 |
24396070 |
10 |
FOS |
Up |
mRNA and protein |
RT-PCR, northern blot (mouse and rat), Immunohistochemistry, Western blot |
Mouse, rat, human |
3T3 cells, Adipocytes, ENU1564 cell, Astrocytes of periventricular zone of third ventricle, SUM-52PE cells |
16309174, 2507555, 18041768, 11172932, 20388777 |
|
|
|
11 |
JUN |
Up |
mRNA and protein |
RT-PCR, Western blot |
Rat |
ENU1564 cells |
18041768 |
|
|
|
12 |
JUNB |
Up |
mRNA and protein |
Gene chip array (Rat), Western blot |
Rat, human |
Rat Wister bladder tumor cells (NBT-II), SUM-52PE cells |
18189245, 20388777 |
|
|
|
13 |
MDM2 |
Up |
mRNA and protein |
RT-PCR, Western blot |
Rat |
REtsAF cells |
16091747 |
|
|
|
14 |
MMP14 |
Up |
mRNA and protein |
Northern blot, Gene chip array, Western blot |
Human, rat |
Prostate cancer cell line, LNCaP, Rat Wister bladder tumor cells (NBT-II) |
14673954, 18189245 |
STAT3 |
6774 |
14673954 |
15 |
MMP9 |
Up |
mRNA and protein |
RT-PCR, Gene chip array, Western blot |
Rat |
ENU1564 cells, Rat Wister bladder tumor cells (NBT-II) |
18041768, 18189245 |
RELA, JUN, FOS |
5970, 3725, 2353 |
18041768 |
16 |
MYC |
Up |
mRNA and protein |
Northern blot (Mouse), Western blot |
Mouse, human |
3T3 cells, SUM-52PE cells |
16309174, 20388777 |
|
|
|
17 |
NOS2 |
Up |
mRNA and protein |
RT-PCR, Western blot |
Rat |
Astrocytes |
16524372 |
|
|
|
18 |
PLAU |
Up |
mRNA and protein |
RT-PCR, ELISA |
Human |
Fibroblasts |
12008951 |
|
|
|
19 |
PPARG |
Up |
mRNA and protein |
RT-PCR, Western blot |
Human, mouse |
Preadipocytes, 3T3-L1 cells |
17068114, 22187378 |
|
|
|
20 |
SLC2A4 |
Up |
mRNA and protein |
RT-PCR, Western blot |
Human, mouse |
Preadipocytes, 3T3-L1 cells |
22187378, 17068114 |
|
|
|
21 |
THY1 |
Up |
mRNA and protein |
Northern blot, Western blot |
Rat |
PC12 cell lines |
11084019 |
|
|
|
22 |
TNFRSF12A |
Up |
mRNA and protein |
RT-PCR, Immunoblot |
Rat |
Cardiomyocytes |
19629561 |
|
|
|
23 |
NGF |
Up |
mRNA and Protein |
RT-PCR, Enzyme Immuno assay |
Rat |
Hippocampal astrocytes, skin fibroblasts, Primary spinal cord astrocyte |
1377078, 15773903 |
|
|
|
24 |
VEGFA |
Up |
mRNA and protein |
Real time PCR, ELISA |
Human |
Primary human airway smooth muscle cells |
22205500 |
|
|
|
25 |
ACPL2 |
Down |
mRNA |
Microarray |
Mouse |
Osteoblast cells |
18505824 |
|
|
|
26 |
ARG1 |
Up |
mRNA |
Gene chip array, Q-PCR |
Rat |
Rat Wister bladder tumor cells (NBT-II) |
18189245 |
|
|
|
27 |
ATP2A2 |
Up |
mRNA |
RNA gel blot |
Mouse |
NIH 3T3 cells |
7506544 |
|
|
|
28 |
AXIN2 |
Down |
mRNA |
Microarray |
Mouse |
Osteoblast cells |
18505824 |
|
|
|
29 |
BGLAP |
Up |
mRNA |
in situ hybridization |
Mouse |
Mouse calvaria cells (coronal sutures) |
12674336 |
|
|
|
30 |
CTSC |
Up |
mRNA |
Gene chip array |
Rat |
Rat wister bladder tumor cells (NBT-II) |
18189245 |
|
|
|
31 |
DKK3 |
Down |
mRNA |
Microarray |
Mouse |
Osteoblast cells |
18505824 |
|
|
|
32 |
DLL1 |
Down |
mRNA |
Northern blot |
Mouse |
Neuroepithelial precursor (E10) |
11466430 |
|
|
|
33 |
DUSP1 |
Up |
mRNA |
Gene chip array |
Rat |
Rat Wister bladder tumor cells (NBT-II) |
18189245 |
|
|
|
34 |
DYNC2LI1 |
Up |
mRNA |
Gene chip array |
Rat |
Rat Wister bladder tumor cells (NBT-II) |
18189245 |
|
|
|
35 |
EDNRA |
Up |
mRNA |
Northern blot |
Rat |
Arterial smooth muscle cells |
12851419 |
|
|
|
36 |
EFNB1 |
Up |
mRNA |
Gene chip array |
Rat |
Rat Wister bladder tumor cells (NBT-II) |
18189245 |
|
|
|
37 |
ELF4 |
Up |
mRNA |
Gene chip array |
Rat |
Rat Wister bladder tumor cells (NBT-II) |
18189245 |
|
|
|
38 |
FASN |
Up |
mRNA |
RNA gel blot |
Mouse |
NIH 3T3 cells |
7506544 |
|
|
|
39 |
FGF1 |
Up |
mRNA |
RT-PCR |
Rat |
Pheochromocytoma cells |
8576258 |
|
|
|
40 |
FGF7 |
Up |
mRNA |
RT-PCR |
Mouse |
Embryonic lung mesenchymal cells |
10446271 |
|
|
|
41 |
FN1 |
Up |
mRNA |
Gene chip array |
Rat |
Rat Wister bladder tumor cells (NBT-II) |
18189245 |
|
|
|
42 |
FZD1 |
Down |
mRNA |
Microarray |
Mouse |
Osteoblast cells |
18505824 |
|
|
|
43 |
FZD2 |
Down |
mRNA |
Microarray |
Mouse |
Osteoblast cells |
18505824 |
|
|
|
44 |
FZD7 |
Down |
mRNA |
Microarray |
Mouse |
Osteoblast cells |
18505824 |
|
|
|
45 |
FZD8 |
Down |
mRNA |
Microarray |
Mouse |
Osteoblast cells |
18505824 |
|
|
|
46 |
F3 |
Down |
mRNA |
Northern blot |
Human |
Human umbilical vein endothelial cells |
9157959 |
|
|
|
47 |
GADD45A |
Down |
mRNA |
Microarray |
Mouse |
Osteoblast cells |
18505824 |
|
|
|
48 |
HBEGF |
Up |
mRNA |
Gene chip array |
Rat |
Rat Wister bladder tumor cells (NBT-II) |
18189245 |
|
|
|
49 |
HMGA2 |
Down |
mRNA |
Northern blot |
Rat |
3T3-L1 cells |
10490844 |
|
|
|
50 |
IBSP |
Up |
mRNA |
in situ hybridization |
Mouse |
Mouse calvaria cells (coronal sutures) |
12674336 |
|
|
|
51 |
IGF1 |
Down |
mRNA |
RT-PCR |
Human |
Fibroblasts |
12008951 |
|
|
|
52 |
IGF2 |
Down |
mRNA |
RT-PCR |
Human |
Fibroblasts |
12008951 |
|
|
|
53 |
IGF1R |
Down |
mRNA |
RT-PCR |
Human |
Fibroblasts |
12008951 |
|
|
|
54 |
IGF2R |
Down |
mRNA |
RT-PCR |
Human |
Fibroblasts |
12008951 |
|
|
|
55 |
IGFBP4 |
Down |
mRNA |
RT-PCR |
Human |
Fibroblasts |
12008951 |
|
|
|
56 |
IL4 |
Up |
mRNA |
Q-PCR |
Rat |
Transected spinal cord tissue |
21411654 |
|
|
|
57 |
IRS1 |
Down |
mRNA |
Microarray |
Mouse |
Osteoblast cells |
18505824 |
|
|
|
58 |
LAMA3 |
Up |
mRNA |
Gene chip array |
Rat |
Rat Wister bladder tumor cells (NBT-II) |
18189245 |
|
|
|
59 |
LRRC17 |
Down |
mRNA |
Microarray |
Mouse |
Osteoblast cells |
18505824 |
|
|
|
60 |
MITF |
Up |
mRNA |
Microarray |
Mouse |
Osteoblast cells |
18505824 |
|
|
|
61 |
MMP13 |
Up |
mRNA |
Gene chip array, Q-PCR |
Rat |
Rat Wister bladder tumor cells (NBT-II) |
18189245 |
|
|
|
62 |
MMP3 |
Up |
mRNA |
Northern blot |
Rat |
PC12 cell lines |
11084019 |
|
|
|
63 |
MSH6 |
Up |
mRNA |
RNA gel blot |
Mouse |
NIH 3T3 cells |
8870641 |
|
|
|
64 |
MSX2 |
Up |
mRNA |
in situ hybridization |
Mouse |
Mouse calvaria cells |
12674336 |
|
|
|
65 |
NID2 |
Up |
mRNA |
Gene chip array |
Rat |
Rat Wister bladder tumor cells (NBT-II) |
18189245 |
|
|
|
66 |
NOTCH1 |
Up |
mRNA |
Northern blot, Gene chip array, Q-PCR |
Mouse, rat |
Neuroepithelial precursor (E10), bladder tumor cells (NBT-II) |
11466430, 18189245 |
|
|
|
67 |
NR1H3 |
Up |
mRNA |
RT-PCR |
Rat |
Astrocytes |
19229075 |
|
|
|
68 |
ODC1 |
Up |
mRNA |
Northern blot |
Mouse |
NIH 3T3 cells |
9223379 |
|
|
|
69 |
PDGFA |
Up |
mRNA |
RNA gel blot |
Human |
HUVE cells |
1689299 |
|
|
|
70 |
PFKL |
Up |
mRNA |
RNA gel blot |
Mouse |
NIH 3T3 cells |
7506544 |
|
|
|
71 |
PLAT |
Up |
mRNA |
RT-PCR |
Human |
Fibroblasts |
12008951 |
|
|
|
72 |
PLAUR |
Up |
mRNA |
RT-PCR |
Human |
Fibroblasts |
12008951 |
|
|
|
73 |
PLF |
Up |
mRNA |
Northern blot |
Mouse |
NIH 3T3 cells |
9223379 |
|
|
|
74 |
PMEPA1 |
Down |
mRNA |
Microarray |
Mouse |
Osteoblast cells |
18505824 |
|
|
|
75 |
PNRC1 |
Up |
mRNA |
Gene chip array |
Rat |
Rat Wister bladder tumor cells (NBT-II) |
18189245 |
|
|
|
76 |
POSTN |
Up |
mRNA |
Northern blot |
Rat |
Pulmonary arterial smooth muscle cells |
15121739 |
|
|
|
77 |
PPIA |
Up |
mRNA |
Northern blot |
Rat |
PC12 cell lines |
11084019 |
|
|
|
78 |
PRICKLE1 |
Down |
mRNA |
Microarray |
Mouse |
Osteoblast cells |
18505824 |
|
|
|
79 |
PRPH |
Up |
mRNA |
Northern blot |
Rat |
PC12 cell lines |
11084019 |
|
|
|
80 |
PTPRE |
Up |
mRNA |
Gene chip array |
Rat |
Rat Wister bladder tumor cells (NBT-II) |
18189245 |
|
|
|
81 |
RUNX2 |
Up |
mRNA |
in situ hybridization |
Mouse |
Mouse calvaria cells (coronal sutures) |
12674336 |
|
|
|
82 |
SCGB1A1 |
Up |
mRNA |
RT-PCR |
Mouse |
Mouse lung epithelium |
12242715 |
|
|
|
83 |
SDC1 |
Up |
mRNA |
Gene chip array |
Rat |
Rat Wister bladder tumor cells (NBT-II) |
18189245 |
|
|
|
84 |
SERPINB1 |
Down |
mRNA |
Microarray |
Mouse |
Osteoblast cells |
18505824 |
|
|
|
85 |
SERPINB2 |
Up |
mRNA |
RT-PCR |
Human |
Fibroblasts |
12008951 |
|
|
|
86 |
SERPINE1 |
Up |
mRNA |
RT-PCR |
Human |
Fibroblasts |
12008951 |
|
|
|
87 |
SFRP1 |
Down |
mRNA |
Microarray |
Mouse |
Osteoblast cells |
18505824 |
|
|
|
88 |
SFTPC |
Up |
mRNA |
RT-PCR |
Mouse |
Mouse lung epithelium, Embryonic stem cell (mESC) line E14-Tg2a |
12242715, 20497026 |
|
|
|
89 |
SOCS1 |
Up |
mRNA |
Northern blot |
Rat |
Mouse lens epithelium |
14985304 |
|
|
|
90 |
SOCS3 |
Up |
mRNA |
Northern blot |
Rat |
Mouse lens epithelium |
14985304 |
|
|
|
91 |
SOX2 |
Up |
mRNA |
Microarray |
Mouse |
Osteoblast cells |
18505824 |
|
|
|
92 |
SPP1 |
Up |
mRNA |
Quantitative northern blot |
Rat |
Pulmonary arterial smooth muscle cells |
15121739 |
|
|
|
93 |
SPRY1 |
Up |
mRNA |
RNA gel blot |
Mouse |
MC3T3-E1 osteoblasts |
16604287 |
|
|
|
94 |
SPRY2 |
Up |
mRNA |
RNA gel blot |
Mouse |
MC3T3-E1 osteoblasts |
16604287 |
|
|
|
95 |
SPRY4 |
Up |
mRNA |
RNA gel blot |
Mouse |
MC3T3-E1 osteoblasts |
16604287 |
|
|
|
96 |
S1PR3 |
Up |
mRNA |
Northern blot |
Human |
Human umbilical vein endothelial cells |
9315732 |
|
|
|
97 |
TCF3 |
Down |
mRNA |
Microarray |
Mouse |
Osteoblast cells |
18505824 |
|
|
|
98 |
TCF4 |
Down |
mRNA |
RT-PCR |
Human |
Preadipocytes |
22187378 |
|
|
|
99 |
TGFA |
Up |
mRNA |
Northern blot |
Mouse |
Cultured keratinocytes |
7535082 |
|
|
|
100 |
TGFB2 |
Down |
mRNA |
Microarray |
Mouse |
Osteoblast cells |
18505824 |
|
|
|
101 |
TGFBR3 |
Down |
mRNA |
Microarray |
Mouse |
Osteoblast cells |
18505824 |
|
|
|
102 |
THBS1 |
Down |
mRNA |
Microarray |
Mouse |
Osteoblast cells |
18505824 |
|
|
|
103 |
THBS1 |
Up |
mRNA |
Northern blot |
Mouse |
NIH 3T3 cells |
9223379 |
|
|
|
104 |
TIMP1 |
Up |
mRNA |
Gene chip array |
Rat |
Rat Wister bladder tumor cells (NBT-II) |
18189245 |
|
|
|
105 |
TIMP3 |
Down |
mRNA |
Microarray |
Mouse |
Osteoblast cells |
18505824 |
|
|
|
106 |
VIM |
Up |
mRNA |
Gene chip array |
Rat |
Rat Wister bladder tumor cells (NBT-II) |
18189245 |
|
|
|
107 |
ADIPOQ |
Up |
Protein |
Radioimmunoassay |
Human |
Preadipocytes |
17068114 |
|
|
|
108 |
CCNE1 |
Up |
Protein |
Western blot |
Human |
MG63 osteoblastic cells |
15572039 |
|
|
|
109 |
CTNNB1 |
Down |
Protein |
Western blot |
Human |
Simpson Golabi Behmel syndrome (SGBS), Preadipocytes |
22187378 |
|
|
|
110 |
HMOX1 |
Up |
Protein |
Western blot |
Human |
Spinal cord astrocytes |
16524372 |
|
|
|
111 |
MMP7 |
Up |
Protein |
ELISA |
Human |
LNCaP cells |
11922392 |
STAT3 |
6774 |
11922392 |
112 |
PKMYT1 |
Up |
Protein |
Immunoblot |
Rat |
Chondrosarcoma cells |
21051949 |
|
|
|
113 |
PLIN1 |
Up |
Protein |
Western blot |
Human, mouse |
Preadipocytes, 3T3-L1 cells |
17068114 |
|
|
|
114 |
PTGIS |
Down |
Protein |
ELISA |
Human |
Endothelial cells |
2107185 |
|
|
|
115 |
PTGS2 |
Down |
Protein |
ELISA |
Human |
Endothelial cells |
2107185 |
|
|
|
116 |
RELA |
Up |
Protein |
Western blot |
Rat |
ENU1564 cells |
18041768 |
|
|
|
117 |
RHOA |
Up |
Protein |
Immunoblot |
Rat |
Cardiomyocytes |
19629561 |
|
|
|
118 |
SOX9 |
Up |
Protein |
Western blot |
Mouse |
Costal chondrocytes |
10655493 |
|
|
|
119 |
WEE1 |
Up |
Protein |
Immunoblot |
Rat |
Chondrosarcoma cells |
21051949 |
|
|
|
120 |
CDH2 |
Up |
Protein |
Western blot |
Rat |
PC12 cells |
24396070 |
STAT3, SP1 |
6774, 6667 |
24396070 |
121 |
GAP43 |
Up |
Protein |
Western blot |
Rat |
PC12 cells |
24396070 |
STAT3 |
6774 |
24396070 |