Figure 2.

Histological sections of cerebral white matter of pseudotumoral multiple sclerosis. (a) Increased cellularity of the white matter due to infiltration by macrophages. Hematoxylin-eosin. (b) Junction of the normal (left) and demyelinated white matter (right), showing the well-defined limits of the demyelinated area. Luxol fast blue. (c) Relative axonal preservation in the demyelinated area. Immunohistochemistry for neurofilament. (d) Diffuse and perivascular infiltration (arrow) by macrophages. Immunohistochemistry for CD68.