Table 3.
Parameters | S + CA | S + SP | F + CA | F + SP | Two-way ANOVA | ||
---|---|---|---|---|---|---|---|
CARB | PROT | INTER | |||||
Glucose (mg/dL) | 92.4 ± 5.8a | 86.4 ± 4.1a | 202.5 ± 16.9b | 112.8 ± 9.51c | P < 0.0001 | P < 0.0001 | P < 0.0001 |
Insulin (μIU/mL) | 17.2 ± 0.7a | 16.9 ± 0.8a | 30.5 ± 2.4b | 19.3 ± 1.5c | P < 0.0001 | P < 0.0001 | P < 0.0001 |
Glycated hemoglobin (mg/g Hb) | 0.35 ± 0.01a | 0.34 ± 0.02a | 0.83 ± 0.04b | 0.40 ± 0.02d | P < 0.0001 | P < 0.0001 | P < 0.0001 |
Fructosamine (mmol/L) | 0.47 ± 0.02a | 0.48 ± 0.03a | 1.3 ± 0.10b | 0.54 ± 0.03a | P < 0.0001 | P < 0.0001 | P < 0.0001 |
AOPP (μmol/L) | 90.6 ± 4.6a | 65.8 ± 2.8a | 160.5 ± 8.2b | 110.18 ± 5.3c | P < 0.0001 | P < 0.0001 | P < 0.0001 |
FRAP (μmol/L) | 990.3 ± 3.8a | 1076.2 ± 2.5a | 770.4 ± 3.3b | 956.6 ± 3.9c | P < 0.0001 | P < 0.0001 | P < 0.0001 |
Intracellular ROS generation in liver (mean fluorescence intensity) | 343 ± 2.7a | 339 ± 1.8a | 583 ± 4.1b | 352 ± 2.3c | P < 0.0001 | P < 0.0001 | P < 0.0001 |
Data are means ± SD of 6 rats from each group. S + CA: starch + casein diet-fed rats; S + SP: starch + soy protein diet-fed rats; F + CA: fructose + casein diet-fed rats; F + SP: fructose + soy protein diet-fed rats. NS: not significant; CARB: carbohydrate; PROT: protein; INTER: interaction; ROS: reactive oxygen species; AOPP: advanced oxidation protein products; FRAP: ferric reducing antioxidant power. Values that bear different superscripts are significantly different from each other [one-way ANOVA followed by Tukey's test (P < 0.05)].