Table 3. Tabulation of exact gyral anatomic localization of regionally decreased CVR and corresponding decreased or absent expected sensorimotor activation as well as correlation with clinical functional status to determine whether findings are indicative of true NVU.
Patient # | Gyrus displaying Ipsilesional decreased/absent motor activation corresponding to decreased CVR | Functional area Associated with Involved gyrus | Actual NVU(i.e., false Negative activation)? Yes/No | How clinical functional determination was made of false negative vs. true negative activation |
---|---|---|---|---|
1 | L precentral gyrus | Face RA) of (PMC) | N | R facial droop |
2 | L precentral gyrus | Hand and more prominently face RA of PMC | Y | No motor deficit |
3 | R precentral gyrus | Face RA of PMC | Y | No face or other motor deficit |
4 | R precentral gyrus | Foot RA of PMC | Y | No left lower Extremity weakness |
5 | Left precentral gyrus | Hand RA of PMC | Y | No motor deficit despite asymmetrically decreased hand motor activation |
6 | R precentral gyrus | Face RA of PMC | Y | No face or other motor deficit |
7 | L superior frontal gyrus | L SMA | Y | No motor or language deficit |
8 | R postcentral gyrus | Hand RA of (PSC) | N | Mild left upper extremity sensory deficit |
9 | R superior frontal gyrus, superior aspect of R precentral gyrus | Foot RA of PMC, R SMA | N | Severe left lower extremity weakness |
10 | R postcentral gyrus | Face/tongue RA of PSC | Y | No sensory deficits |
11 | R superior frontal gyrus, superomedial aspect of right precentral gyrus | R SMA, R foot RA of PMC | Y | No motor or sensory deficits preoperatively |
12 | R precentral gyrus, R superior frontal gyrus | Foot RA of PMC and R SMA | Y | No motor deficit |
CVR: cerebrovascular reactivity; NVU: neurovascular uncoupling; L: Left; R: Right; RA: Representation area; PMC: Primary Motor Cortex; SMA: Supplementary Motor Area; PSC: Primary Somatosensory Cortex