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. Author manuscript; available in PMC: 2014 May 4.
Published in final edited form as: Annu Rev Pathol. 2013 Sep 25;9:287–314. doi: 10.1146/annurev-pathol-012513-104715

Figure 2. miRNAs dysregulation in cancer.

Figure 2

The canonical miRNA biogenesis pathway and miR-RISC activity are schematically represented. In red, steps commonly deregulated in cancer are reported and visually associated to the miRNA dysregulation identified in cancer. RNA binding protein abbreviated as RBP. ceRNAs represented in blue. CH3, methylation; Ac, acetylation.