Fig. 5.
Gross and histopathologic changes in the lungs infected with CIV. Gross lesion and hematoxylin-and-eosin-stained lung sections (scale bar= 100 μm) from dogs at 4 days post infection are shown. (A) and (E), unvaccinated dog. (B) and (F), dog vaccinated with 3.75 μg of CIV H3 HA VLP. (C) and (G), dog vaccinated with 7.5 μg of CIV H3 HA VLP. (D) and (H), dog vaccinated with 15 μg of CIV H3 HA VLP.