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. Author manuscript; available in PMC: 2015 May 28.
Published in final edited form as: Neuroreport. 2014 May 28;25(8):580–584. doi: 10.1097/WNR.0000000000000140

Table 2A.

Association between TLR4 SNP (1063 A/G [Asp299Gly] and/or 1363 C/T [Thr399Ile]) and poor outcome (modified Rankin Scale score >2) at 3 months post AIS.

Presence of TLR4 SNP predicts poor outcome
model adjusted for: OR
(95% CI)		 P
TLR4 SNP * 2.21 (0.58-8.38) 0.24
TLR4 SNP+NIHSS 9.22 (1.43-59.5`) 0.02
TLR4 SNP+NIHSS + age 12.92 (1.78-93.90) 0.01
TLR4 SNP + NIHSS + age + stroke etiology 15.46 (2.04-117.04) 0.008
TLR4 SNP + NIHSS + age + stroke etiology + infection 14.16 (1.75-114.81) 0.01
*

Numerical breakdown of unadjusted data:

99/113 (88%) of patients in study had outcome data available at this time point.

42/99 (42%) of patients with available outcome data at this time point had poor outcome.

6/10 (60%) of patients with available outcome data at this time point and a TLR4 SNP had a poor outcome

36/89 (40%) of patients with available outcome data at this time point without a TLR4 SNP had a poor outcome